| 12:00 PM | Indiana @ 9 Penn State | ABC | Jason Benetti, Rod Gilmore, Quint Kessenich |
| 12:00 PM | 11 Florida @ Missouri | CBS | Carter Blackburn, Aaron Taylor, Rick Neuheisel |
| 12:00 PM | Michigan State @ 15 Michigan | FOX | Gus Johnson, Joel Klatt |
| 12:00 PM | 5 Alabama @ Mississippi State | ESPN | Steve Levy, Brian Griese, Todd McShay |
| 12:00 PM | TCU @ Texas Tech | ESPN2 | Dave Neal, DJ Shockley |
| 12:00 PM | Kansas @ 22 Oklahoma State | FS1 | Dan Hellie, Ben Leber |
| 12:00 PM | Tulane @ Temple | ESPNU | Kevin Brown, Andre Ware |
| 12:00 PM | 14 Wisconsin @ Nebraska | BTN | Kevin Kugler, Matt Millen |
| 12:00 PM | Massachusetts @ Northwestern | BTN | Lisa Byington, J Leman |
| 12:00 PM | VMI @ Army | CBSSN | Ben Holden, Ross Tucker |
| 12:00 PM | Alabama State @ Florida State | ACC RSNs | Tom Werme, James Bates |
| 1:00 PM | UTEP @ UAB | ESPN3 | |
| 2:30 PM | 23 Navy @ 16 Notre Dame | NBC | Mike Tirico, Doug Flutie |
| 3:00 PM | Idaho State @ BYU | BYU TV | Dave McCann, Blaine Fowler |
| 3:00 PM | Coastal Carolina @ Arkansas State | ESPN+ | |
| 3:00 PM | ULM @ Georgia Southern | ESPN+ | |
| 3:00 PM | Troy @ Texas State | ESPN3 | |
| 3:30 PM | Wake Forest @ 3 Clemson | ABC | Bob Wischusen, Dan Orlovsky |
| 3:30 PM | 4 Georgia @ 12 Auburn | CBS | Brad Nessler, Gary Danielson |
| 3:30 PM | West Virginia @ 24 Kansas State | ESPN | Mark Jones, Dusty Dvoracek |
| 3:30 PM | 18 Memphis @ Houston | ESPN2 | Beth Mowins, Anthony Becht, Rocky Boiman |
| 3:30 PM | 19 Texas @ Iowa State | FS1 | Brian Custer, Robert Smith |
| 3:30 PM | Kentucky @ Vanderbilt | SECN | Taylor Zarzour, Matt Stinchcomb |
| 3:30 PM | 2 Ohio State @ Rutgers | BTN | Brandon Gaudin, James Laurinaitis |
| 3:30 PM | Central Michigan @ Ball State | CBSSN | John Sadak, Randy Cross |
| 3:30 PM | Virginia Tech @ Georgia Tech | ACC RSNs | Evan Lepler, Dave Archer |
| 4:00 PM | 8 Minnesota @ 20 Iowa | FOX | Joe Davis, Brock Huard |
| 4:00 PM | Wyoming @ Utah State | ESPNU | Mike Couzens, Kirk Morrison |
| 4:00 PM | Syracuse @ Duke | ACCN | Wes Durham, Roddy Jones, Eric Wood |
| 4:00 PM | Hawaii @ UNLV | Hawaii PPV,
Stadium (Facebook) | |
| 4:00 PM | Incarnate Word @ New Mexico State | FSN Ariz+, FloSports | |
| 4:30 PM | Stanford @ Washington State | P12N | Ted Robinson, Yogi Roth |
| 4:30 PM | Rice @ Middle Tennessee | ESPN+ | |
| 5:00 PM | ULL @ South Alabama | ESPN+ | |
| 6:00 PM | Southern Mississippi @ UTSA | ESPN+ | |
| 7:00 PM | 1 LSU @ Ole Miss | ESPN | Sean McDonough, Todd Blackledge |
| 7:00 PM | Air Force @ Colorado State | ESPN2 | Roy Philpott, Kelly Stouffer |
| 7:00 PM | 17 Cincinnati @ South Florida | CBSSN | Rich Waltz, Corey Chavous |
| 7:30 PM | 10 Oklahoma @ 13 Baylor | ABC | Chris Fowler, Kirk Herbstreit |
| 7:30 PM | Arizona State @ Oregon State | FS1 | Aaron Goldsmith, Jordan Palmer |
| 7:30 PM | 25 Appalachian State @ Georgia State | ESPNU | Clay Matvick, Ryan Leaf |
| 7:30 PM | South Carolina @ Texas A&M | SECN | Tom Hart, Jordan Rodgers, Cole Cubelic |
| 7:30 PM | Louisville @ N.C. State | ACCN | Dave O’Brien, Tim Hasselbeck |
| 8:00 PM | UCLA @ 7 Utah | FOX | Tim Brando, Spencer Tillman |
| 10:15 PM | New Mexico @ 21 Boise State | ESPN2 | Mike Corey, Rene Ingoglia |
| 10:30 PM | Arizona @ 6 Oregon | ESPN | Dave Pasch, Greg McElroy, Tom Luginbill |
| 11:00 PM | USC @ California | FS1 | Cory Provus, Shane Vereen, Petros Papadakis |
