| 12:00 PM | 10 Minnesota @ Northwestern | ABC | Bob Wischusen, Dan Orlovsky |
| 12:00 PM | 8 Penn State @ 2 Ohio State | FOX | Gus Johnson, Joel Klatt |
| 12:00 PM | Western Carolina @ 5 Alabama | ESPN | Roy Philpott, Kelly Stouffer |
| 12:00 PM | 21 Oklahoma State @ West Virginia | ESPN2 | Beth Mowins, Anthony Becht, Rocky Boiman |
| 12:00 PM | Michigan State @ Rutgers | FS1 | John Strong, Evan Moore |
| 12:00 PM | Samford @ 15 Auburn | SECN | Taylor Zarzour, Matt Stinchcomb |
| 12:00 PM | Illinois @ 17 Iowa | BTN | Kevin Kugler, Matt Millen |
| 12:00 PM | UCF @ Tulane | CBSSN | Ben Holden, Ross Tucker |
| 12:00 PM | Kansas @ 22 Iowa State | FSN regional | Mark Followill, Jordan Palmer |
| 12:00 PM | Liberty @ Virginia | ACC RSNs | Evan Lepler, Dave Archer |
| 12:00 PM | BYU @ Massachusetts | NESN, FloSports | |
| 12:00 PM | Ball State @ Kent State | ESPN+ | |
| 12:00 PM | East Carolina @ Connecticut | ESPN3 | Robert Lee, Matt Chatham |
| 2:00 PM | South Alabama @ Georgia State | ESPN+ | |
| 2:00 PM | Air Force @ New Mexico | ESPN3 | |
| 2:30 PM | Boston College @ 16 Notre Dame | NBC | Mike Tirico, Doug Flutie |
| 2:30 PM | Texas State @ 24 Appalachian State | ESPN+ | |
| 3:00 PM | Georgia Southern @ Arkansas State | ESPN+ | |
| 3:30 PM | UCLA @ 23 USC | ABC | Steve Levy, Brian Griese, Todd McShay |
| 3:30 PM | Texas A&M @ 4 Georgia | CBS | Brad Nessler, Gary Danielson |
| 3:30 PM | 13 Michigan @ Indiana | ESPN | Sean McDonough, Todd Blackledge |
| 3:30 PM | Pittsburgh @ Virginia Tech | ESPN2 | Mark Jones, Dusty Dvoracek |
| 3:30 PM | Texas @ 14 Baylor | FS1 | Brian Custer, Robert Smith |
| 3:30 PM | UT-Martin @ Kentucky | SECN | Dave Neal, DJ Shockley |
| 3:30 PM | East Tennessee State @ Vanderbilt | SECN (alt) | Dave Lamont, Ray Bentley |
| 3:30 PM | Nebraska @ Maryland | BTN | Brandon Gaudin, James Laurinaitis |
| 3:30 PM | 25 Southern Methodist @ Navy | CBSSN | John Sadak, Randy Cross |
| 3:30 PM | Mercer @ North Carolina | ACC RSNs | Tom Werme, James Bates |
| 3:30 PM | North Texas @ Rice | NFLN | Dan Hellie, Michael Robinson |
| 3:30 PM | Marshall @ Charlotte | Stadium (Facebook) | |
| 3:30 PM | Louisiana Tech @ UAB | ESPN+ | |
| 3:30 PM | Western Kentucky @ Southern Mississippi | ESPN+ | |
| 4:00 PM | Purdue @ 12 Wisconsin | FOX | Tim Brando, Spencer Tillman |
| 4:00 PM | 18 Memphis @ South Florida | ESPNU | Clay Matvick, Ryan Leaf |
| 4:00 PM | California @ Stanford | P12N | Ted Robinson, Yogi Roth |
| 4:00 PM | Syracuse @ Louisville | ACCN | Chris Cotter, Mark Herzlich |
| 4:00 PM | San Jose State @ UNLV | AT&T Sports (RM),
MWC Digital | Drew Goodman, Sed Bonner |
| 4:00 PM | UTEP @ New Mexico State | FSN Ariz+, FloSports | |
| 4:30 PM | Old Dominion @ Middle Tennessee | ESPN3 | |
| 5:00 PM | Troy @ ULL | ESPN+ | |
| 5:00 PM | Coastal Carolina @ ULM | ESPN3 | |
| 6:00 PM | FAU @ UTSA | ESPN+ | |
| 7:00 PM | Arkansas @ 1 LSU | ESPN | Dave Pasch, Greg McElroy, Tom Luginbill |
| 7:00 PM | Temple @ 19 Cincinnati | ESPN2 | Anish Shroff, John Congemi |
| 7:00 PM | Kansas State @ Texas Tech | FS1 | Aaron Goldsmith, Ben Leber |
| 7:00 PM | Miami vs FIU | CBSSN | Rich Waltz, Aaron Murray |
| 7:30 PM | 6 Oregon @ Arizona State | ABC | Chris Fowler, Kirk Herbstreit |
| 7:30 PM | Houston @ Tulsa | ESPNU | Kevin Brown, Andre Ware |
| 7:30 PM | Tennessee @ Missouri | SECN | Tom Hart, Jordan Rodgers, Cole Cubelic |
| 7:30 PM | Abilene Christian @ Mississippi State | SECN (alt) | Mark Neely, Hudson Mason |
| 7:30 PM | Duke @ Wake Forest | ACCN | Dave O’Brien, Tim Hasselbeck |
| 8:00 PM | TCU @ 9 Oklahoma | FOX | Joe Davis, Brock Huard |
| 9:00 PM | Oregon State @ Washington State | P12N | Roxy Bernstein, Anthony Herron |
| 10:00 PM | Washington @ Colorado | ESPN | Jason Benetti, Rod Gilmore, Quint Kessenich |
| 10:00 PM | 7 Utah @ Arizona | FS1 | Cory Provus, Shane Vereen, Petros Papadakis |
| 10:30 PM | Nevada @ Fresno State | ESPN2 | Mike Couzens, Kirk Morrison |
| 10:30 PM | 20 Boise State @ Utah State | CBSSN | Carter Blackburn, Aaron Taylor |
| 11:59 PM | San Diego State @ Hawaii | Hawaii PPV,
Stadium (Facebook) | |
