| 12:00 PM | 6 Oklahoma @ Kansas | ABC | Dave Pasch, Greg McElroy, Tom Luginbill |
| 12:00 PM | 14 Iowa @ 19 Michigan | FOX | Gus Johnson, Joel Klatt |
| 12:00 PM | Purdue @ 12 Penn State | ESPN | Bob Wischusen, Dan Orlovsky |
| 12:00 PM | TCU @ Iowa State | ESPN2 | Roy Philpott, Kelly Stouffer |
| 12:00 PM | 21 Oklahoma State @ Texas Tech | FS1 | Brian Custer, Robert Smith |
| 12:00 PM | Kent State @ 8 Wisconsin | ESPNU | Clay Matvick, Ryan Leaf |
| 12:00 PM | Utah State @ 5 LSU | SECN | Dave Neal, DJ Shockley |
| 12:00 PM | Maryland @ Rutgers | BTN | Lisa Byington, James Laurinaitis |
| 12:00 PM | Tulane @ Army | CBSSN | Ben Holden, Ross Tucker |
| 12:00 PM | South Florida @ Connecticut | cbssports.com* | Rich Waltz, Aaron Murray |
| 12:30 PM | Boston College @ Louisville | ACC RSNs | Tom Werme, James Bates |
| 3:00 PM | Eastern Michigan @ Central Michigan | ESPN+ | |
| 3:30 PM | 11 Texas @ West Virginia | ABC | Steve Levy, Brian Griese, Todd McShay |
| 3:30 PM | 7 Auburn @ 10 Florida | CBS | Brad Nessler, Gary Danielson |
| 3:30 PM | Bowling Green @ 9 Notre Dame | NBC | Mike Tirico, Doug Flutie |
| 3:30 PM | Virginia Tech @ Miami | ESPN | Mark Jones, Dusty Dvoracek |
| 3:30 PM | Baylor @ Kansas State | ESPN2 | Beth Mowins, Anthony Becht, Rocky Boiman |
| 3:30 PM | Illinois @ Minnesota | BTN | Kevin Kugler, Matt Millen |
| 3:30 PM | Air Force @ Navy | CBSSN | John Sadak, Randy Cross |
| 3:30 PM | Marshall @ Middle Tennessee | CBS Sports Facebook | |
| 3:30 PM | Arkansas State @ Georgia State | ESPN+ | |
| 3:30 PM | Ohio @ Buffalo | ESPN+ | |
| 3:30 PM | Western Michigan @ Toledo | ESPN+ | |
| 3:30 PM | Ball State @ Northern Illinois | ESPN3 | |
| 3:45 PM | Memphis @ ULM | ESPNU | Mike Corey, Rene Ingoglia |
| 4:00 PM | Northwestern @ Nebraska | FOX | Tim Brando, Spencer Tillman |
| 4:00 PM | Troy @ Missouri | SECN | Taylor Zarzour, Matt Stinchcomb |
| 4:00 PM | North Carolina @ Georgia Tech | ACCN | Wes Durham, Roddy Jones, Eric Wood |
| 4:30 PM | Arizona @ Colorado | P12N | Ted Robinson, Yogi Roth |
| 6:00 PM | Western Kentucky @ Old Dominion | ESPN+ | |
| 7:00 PM | 3 Georgia @ Tennessee | ESPN | Sean McDonough, Todd Blackledge |
| 7:00 PM | Rice @ UAB | ESPN+ | |
| 7:00 PM | Massachusetts @ FIU | ESPN3 | |
| 7:30 PM | 25 Michigan State @ 4 Ohio State | ABC | Chris Fowler, Kirk Herbstreit |
| 7:30 PM | Tulsa @ 24 Southern Methodist | ESPNU | Anish Shroff, Ahmad Brooks |
| 7:30 PM | Vanderbilt @ Ole Miss | SECN | Tom Hart, Jordan Rodgers, Cole Cubelic |
| 8:00 PM | California @ 13 Oregon | FOX | Brandon Gaudin, Brock Huard |
| 8:00 PM | Pittsburgh @ Duke | ACCN | Dave O’Brien, Tim Hasselbeck |
| 8:00 PM | Liberty @ New Mexico State | FSN Ariz+, FloSports | |
| 8:00 PM | UTSA @ UTEP | ESPN+ | |
| 9:00 PM | Oregon State @ UCLA | P12N | Roxy Bernstein, Anthony Herron |
| 10:00 PM | San Diego State @ Colorado State | ESPN2 | Mike Couzens, Kirk Morrison |
| 10:30 PM | 15 Washington @ Stanford | ESPN | Jason Benetti, Rod Gilmore, Quint Kessenich |
| 10:30 PM | 16 Boise State @ UNLV | CBSSN | Carter Blackburn, Aaron Taylor |
*The USF-UConn game, originally scheduled for 7pm, was moved to noon due to local concerns about the EEE virus. CBS Sports Network will replay the game in its original timeslot. 
